On HowToForge.com there's a new tutorial on how to get the combination of Lighttpd, PHP and MySQL up and running on an OpenSuse linux installation.
Lighttpd is a secure, fast, standards-compliant web server designed for speed-critical environments. This tutorial shows how you can install Lighttpd on an OpenSUSE 11.1 server with PHP5 support (through FastCGI) and MySQL support.
Most of the software installation is handled via packages installed by the "yast2" package manager but you'll still need to go in and modify some of the configuration files to get PHP and Lighttpd to play nicely together. Besides the MySQL package required for PHP's MySQL support, they also suggest getting a few other packages for things like SOAP, SQLite, IMAP, zlib and openssl.